魏玲 ,博士,教授,硕士生导师。主要从事鱼类生殖发育、性别分化、细胞周期调控等方面的研究。主持国家自然科学基金面上项目及青年基金、教育部高等学校博士学科点专项科研基金、重庆市自然科学基金、重庆市基础与前沿研究计划、重庆市博士后科研项目特别资助、中央高校基本科研业务费专项资金等课题。以第一作者或通讯作者在J Genet Genomics、Zool Res、Int J Biol Macromol、Int J Mol Sci、Gene、Mol Biol Rep等期刊发表系列成果;作为合作作者在PNAS、Cell Rep、Nucleic Acids Res、J Biol Chem等期刊发表论文。研究生招生专业为生物化学与分子生物学、动物学,所培养研究生荣获重庆市优秀硕士学位论文等荣誉。
不忘初心,求真务实,认真做好本职工作
教育及研究工作经历
1995-1999,西南农业大学,学士
1999-2002,西南农业大学,硕士
2008-2011,西南大学,博士
2013-2017,西南大学,博士后
2013-2014,美国马里兰大学,访问学者
主要发表论文
[1]Li X#, Tang Y#, Deng W#, Zheng Y, Wang L, He X, Xie Q, Li Y, Deng L, Wang D*,Wei L*. Involvement of Sox9a in chondrogenesis and gonadal development in teleost Nile tilapia (Oreochromisniloticus). Zool Res,2023, 44(4): 729-731
[2] Li Y#, Tang Y#, Wang L#, Li X, Deng L, Deng W, Zheng Y, Wang D*,Wei L*. Transcription factor Sox3 is required for oogenesis in the teleost fish Nile tilapia. Int J Biol Macromol, 2022, 222(Pt B): 2639-2647
[3]Wei L#,*, Tang Y#, Zeng X, Li Y, Zhang S, Deng L, Wang L, Wang D*. The transcription factor Sox30 is involved in Nile tilapia spermatogenesis. J Genet Genomics, 2022, 49(7): 666-676
[4]Tang Y, Li X, Xiao H, Li M, Li Y, Wang D*,Wei L*. Transcription of theSox30gene is positively regulated by Dmrt1 in Nile tilapia. Int J Mol Sci, 2019, 20(21): 5487
[5]Wei L, Li X, Li M, Tang Y, Wei J, Wang D*. Dmrt1 directly regulates the transcription of the testis-biasedSox9bgene in Nile tilapia (Oreochromis niloticus). Gene, 2019, 687: 109-115
[6]Wei L#, Yang C#, Tao W#, Wang D*. Genome-wide identification and transcriptome-based expression profiling of theSoxgene family in the Nile tilapia (Oreochromis niloticus). Int J Mol Sci, 2016,17(3): 270
[7]Wei L#, Li Z#, Cheng D, Kusakabe T, Pan M, Duan J, Wang Y, Lu C*. RNAi silencing of theSoxEgene suppresses cell proliferation in silkworm BmN4 cells. Mol Biol Rep, 2014, 41(7): 4769-4781
[8]Wei L, Cheng D, Li D, Meng M, Peng L, Tang L, Pan M, Xiang Z, Xia Q, Lu C*. Identification and characterization ofSoxgenes in the silkworm,Bombyx mori. Mol Biol Rep, 2011, 38(5): 3573-3584
[9] Li Z#, Qian W#, Song W, Zhao T, Yang Y, Wang W,Wei L, Zhao D, Li Y, Perrimon N*, Xia Q*, Cheng D*. A salivary gland-secreted peptide regulates insect systemic growth. Cell Rep, 2022, 38(8): 110397
[10] Yang Y#, Zhao T#, Li Z, Qian W, Peng J,Wei L, Yuan D, Li Y, Xia Q*, Cheng D*. Histone H3K27 methylation-mediated repression of Hairy regulates insect developmental transition by modulating ecdysone biosynthesis. PNAS, 2021, 118(35): e2101442118
[11] Qian W#, Li Z#, Song W, Zhao T, Wang W, Peng J,Wei L, Xia Q*,Cheng D*. A novel transcriptional cascade is involved in Fzr-mediated endoreplication. Nucleic Acids Res, 2020, 48(8): 4214-4229
[12] Zhang T#, Song W#, Li Z#, Qian W,Wei L, Yang Y, Wang W, Zhou X, Meng M, Peng J, Xia Q*, Perrimon N*, Cheng D*. Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes. PNAS, 2018, 115(15): 3960-3965
[13] Qian W, Gang X, Zhang T,Wei L, Yang X, Li Z, Yang Y, Song L, Wang P, Peng J, Cheng D*, Xia Q*. Protein kinase A-mediated phosphorylation of the Broad-Complex transcription factor in silkworm suppresses its transcriptional activity. J Biol Chem, 2017, 92(30): 12460-12470
[14] Huang X, Zhao Y, Liu L, Fan Z, Zhou L, Wang Z,Wei L, Wang D*, Wei J*. Characterization of the POU5F1 homologue in Nile tilapia: from expression pattern to biological activity. Stem Cells and Development, 2016, 25(18): 1386-1395
[15] Cheng D, Qian W, Wang Y, Meng M,Wei L, Li Z, Kang L, Peng J, Xia Q*. Nuclear import of transcription factor BR-C is mediated by its interaction with RACK1. PLoS One, 2014, 9(10): e109111
联系方式
E-mail:weilchdj@swu.edu.cn,weilingchdj@aliyun.com
地址:重庆市北碚区天生路2号西南大学生命科学学院;邮编:400715