祝顺琴，博士，主要从事植物分子生理生化及细胞生物学方面的研究。主要林木分子育种、珍贵木材培育、植物逆境适应及分子机制研究。主持国家自然科学基金、国家重点研发项目子课题、重庆市林业局示范推广项目、重庆市自然科学基金项目等项目多项。在Plant Journal,Semin Cancer Biol，Phytomedicine,Cell Death Dis等期刊发表论文30余篇。
研究方向
主要聚焦杨树、楠木等经济林木的关键性状遗传解析与逆境生物学研究。重点开展：
（1）林木发育生物学：阐明木材形成及次生发育的分子调控机制。
（2）林木逆境生理机理：解析林木在环境胁迫下的信号感知和防御应答机制。
在研项目情况（2024-至今）
1.国家重点研发子课题，南方主要珍贵用材林定向培育技术，50万，2024.12-2028.11主持
2.重庆市林业局科技推广项目,桢楠林下食用菌栽培模式集成示范与推广，60万，2025.8-2027.7主持
3.林木遗传育种全国重点实验室（中国林业科学研究院）开放课题，杨树组蛋白甲基化转移酶ASHR3改良木材品质研究，6万，2024.6-2026.6.主持
代表性学术论文（#：并列第一作者；*：通讯作者）
1.Song Q, Kong L, Yang J, Lin M, Zhang Y, Yang X, Wang X, Zhao Z, Zhang M, Pan J,Zhu S,Jiao B, Xu C, Luo K. The transcription factor PtoMYB142 enhances drought tolerance in Populus tomentosa by regulating gibberellin catabolism. Plant J. 2024 Apr;118(1):42-57
2.Peng C, Zhang X, Zhou N, Hu T, Shen Y, Chen TJ, Liu Y, Cui H,Zhu S*.Apigenin inhibits lipid metabolism of hepatocellular carcinoma cells by targeting the histone demethylase KDM1A. Phytomedicine. 2024 Dec,135:156024.
3.Zhou N, Yan J, Xiong M,Zhu S*. Decoding the heterogeneous subpopulations of glioblastoma for prognostic stratification and uncovering thepromalignantrole of PSMC2. Sci Rep. 2025,17;15(1):5714.
4.Peng X, Ma T, Song K, Ji X, Xiang L, Chen N, Zu R, Xu W,Zhu S, Liu W. Overexpression ofNtGPX8aImproved Cadmium Accumulation and Tolerance in Tobacco (Nicotiana tabacumL.). Genes (Basel). 2024,15(3):366.
5.Liu W, Yang Y, Hu Y, Peng X, He L, Ma T, Zhu S, Xiang L, Chen N. Overexpression of SQUAMOSA promoter binding protein-like 4a (NtSPL4a) alleviates Cd toxicity in Nicotiana tabacum. PlantPhysiolBiochem. 2024,210:108656.
6.Zhu S#, Gu H#, Peng C, Xia F, Cao H, Cui H*. Regulation of Glucose, Fatty Acid and Amino Acid Metabolism by Ubiquitination and SUMOylation for Cancer Progression. Front Cell Dev Biol. 2022, 21;10:849625.
7.HuoC, He L, Yu T, Ji X, Li R,Zhu S, Zhang F,XieH, Liu W. The Superoxide Dismutase Gene Family inNicotiana tabacum: Genome-Wide Identification, Characterization, Expression Profiling and Functional Analysis in Response to Heavy Metal Stress. Front Plant Sci. 2022,13:904105.
8.Zhu SQ#, Zhang YJ#, Abbas MN, Hao XW, Zhao YZ, Liang HH, Cui HJ, Yang LQ*. Hedgehog promotes cell proliferation in the midgut of silkworm, Bombyx mori. Insect Sci. 2020 Aug;27(4):697-707.
9.An X, Wei Z, Ran B, Tian H, Gu H, Liu Y, Cui H,Zhu S*. Histone Deacetylase InhibitorTrichostatinA Suppresses Cell Proliferation and Induces Apoptosis by Regulating the PI3K/AKT Signalling Pathway in Gastric Cancer Cells. Anticancer Agents Med Chem. 2020;20(17):2114-2124.
10.Zhu S#, Dong Z#,KeX, Hou J, Zhao E, Zhang K, Wang F, Yang L, Xiang Z, Cui H*. The roles ofsirtuinsfamily in cell metabolism during tumor development. Semin Cancer Biol. 2019,57:59-71.
11.Li J, Ye J,Zhu S*,Cui H*. Down-Regulation of Phosphoribosyl Pyrophosphate Synthetase 1 Inhibits Neuroblastoma Cell Proliferation. Cells. 2019 Aug 22;8(9):955.
12.Zhu S, Liu W, Ding HF, Cui H, Yang L. BMP4 and Neuregulin regulate the direction of mouse neural crest cell differentiation. ExpTherMed. 2019 May;17(5):3883-3890.
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联系方式：
重庆市北碚区天生路2号西南大学生命科学学院邮编：400715
电话：023-68253235
Email:zhusq@swu.edu.cn
